Signaling System in Porphyromonas gingivalis Based on a LuxS Protein
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چکیده
منابع مشابه
Signaling system in Porphyromonas gingivalis based on a LuxS protein.
The luxS gene of quorum-sensing Vibrio harveyi is required for type 2 autoinducer production. We identified a Porphyromonas gingivalis open reading frame encoding a predicted peptide of 161 aa that shares 29% identity with the amino acid sequence of the LuxS protein of V. harveyi. Conditioned medium from a late-log-phase P. gingivalis culture induced the luciferase operon of V. harveyi, but tha...
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Communication based on autoinducer 2 (AI-2) is widespread among gram-negative and gram-positive bacteria, and the AI-2 pathway can control the expression of genes involved in a variety of metabolic pathways and pathogenic mechanisms. In the present study, we identified luxS, a gene responsible for the synthesis of AI-2, in Streptococcus gordonii, a major component of the dental plaque biofilm. ...
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متن کاملPorphyromonas gingivalis
Editorial Periodontal diseases have long been associated with an increased, yet moderate, risk for the development of atherosclerosis and coronary heart disease. The postulated mechanism underlying this association is the low grade systemic inflammatory response to pathogens engaged in chronic periodontal infection, such as Porphyromonas gingivalis, which may facilitate atheroma formation and t...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2001
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.183.13.3903-3909.2001